RE: LeoThread 2025-06-03 02:06
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Prostate cancer screening in America needs a major overhaul, leading to the creation of a new company four years ago with the goal to change that.
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A revolutionary urine-based test is nearing completion—simply provide a sample and gain precise results.
Consider these facts:
• More than 20 million PSA tests are performed annually in the U.S.
• Over 70% of positive results turn out to be false alarms, prompting unnecessary biopsies in over 1 million men each year.
• Even when cancer is
present, only about one in three cases actually requires treatment, yet many patients undergo intensive surgeries, radiation, or hormone therapy that adversely affect quality of life.
• Meanwhile, aggressive cancers that truly demand
intervention often remain undetected. The core issue is overtreatment of low-risk cases and missing the dangerous ones.
In collaboration with top-tier scientists and the Mayo Clinic, work has progressed on a test that requires no blood draws or rectal exams, focusing solely on identifying cancers that need care.
Unlike most urine tests that rely on a single biomarker and often yield unreliable results, this test simultaneously assesses proteins and RNAs—proteins to reveal current conditions and RNAs to indicate future developments—resulting in a
much clearer signal. This breakthrough stems from advanced postdoctoral research that now enables detection of multiple biomarkers (DNA, RNA, and proteins) directly from urine.
And this innovation is just the beginning, with a bladder cancer test already in final validation and plans underway to harness this multiomic platform for more accurate diagnostics in various diseases.